Golimumab

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As Golimumab is generally used to treat patients with complications such as rheumatoid arthritis, I used the key word ‘rheumatoid arthritis’ and conducted a search using multiple search engines such as Google and Bing to understand more about it.

For information on Golimumab, I accessed the official site for Simponi® and get to know more in detail about the mechanism of the drug itself to enable me to carry out more intensive research.

I typed in the name of the drug on Google scholar and find scientific journals related to Golimumab to learn more about how it works and how it is produced. By browsing through the journals, I selected a few with the points I found informative and allocate it into my task.

Furthermore, I searched through government websites like www.clinicaltrials.gov to know about the development stage of Golimumab and also www.fda.gov to search for approvals of the drug to be sold to the public.

References

A study of the safety and efficacy of Golimumab (CNTO 148) in subjects with active rheumatoid arthritis previously treated with biologic Anti-TNFa agent(s) - Tabular view (2006) Available at: https://clinicaltrials.gov/ct2/show/record/NCT00299546?view=results (Accessed: 20 March 2016).

Almeida, H., Amaral, M.H. and Lobão, P. (2011) ‘Drugs obtained by biotechnology processing’, Brazilian Journal of Pharmaceutical Sciences, 47(2).

Available at: http://www.scielo.br/pdf/bjps/v47n2/v47n2a02.pdf

(Accessed: 20 March 2016)

CHMP (2009) Simponi, INN: Golimumab. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/000992/WC500052372.pdf (Accessed: 20 March 2016).

How does SIMPONI® work to target and block TNF in moderate to severe RA? – SIMPONI®, 2013 Available at: http://www.simponi.com/rheumatoid-arthritis/learn-about-simponi/how-simponi-works (Accessed: 20 March 2016).

Simponi (golimumab) FDA approval history (2000) Available at: http://www.drugs.com/history/simponi.html (Accessed: 22 March 2016).

What is golimumab and why is it prescribed, 1998, Available at: http://www.arthritisresearchuk.org/arthritis-information/drugs/golimumab/what-it-is.aspx (Viewed: 20 March 2016).